Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.
Identifieur interne : 000021 ( France/Analysis ); précédent : 000020; suivant : 000022Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.
Auteurs : Francoise Pujol [Suède] ; Tina Hodgson [Suède] ; Ines Martinez-Corral [Suède] ; Anne-Catherine Prats [Suède] ; Danelle Devenport [Suède] ; Masatoshi Takeichi [Suède] ; Elisabeth Genot [Suède] ; Taija M Kinen [Suède] ; Philippa Francis-West [Suède] ; Barbara Garmy-Susini [Suède] ; Florence Tatin [France]Source :
- Arteriosclerosis, thrombosis, and vascular biology [ 1524-4636 ] ; 2017.
Descripteurs français
- KwdFr :
- Actines (métabolisme), Animaux, Cadhérines (déficit), Cadhérines (génétique), Cadhérines (métabolisme), Cellules cultivées, Cellules endothéliales (anatomopathologie), Cellules endothéliales (métabolisme), Cytosquelette d'actine (métabolisme), Endothélium lymphatique (anatomopathologie), Endothélium lymphatique (métabolisme), Humains, Lymphangiectasie intestinale (anatomopathologie), Lymphangiectasie intestinale (génétique), Lymphangiectasie intestinale (métabolisme), Lymphangiogenèse, Lymphoedème (anatomopathologie), Lymphoedème (génétique), Lymphoedème (métabolisme), Malformations crâniofaciales (anatomopathologie), Malformations crâniofaciales (génétique), Malformations crâniofaciales (métabolisme), Mouvement cellulaire, Multimérisation de protéines, Mutation, Phénotype, Protéines suppresseurs de tumeurs (génétique), Protéines à fluorescence verte (génétique), Protéines à fluorescence verte (métabolisme), Protéines à homéodomaine (génétique), Prédisposition génétique à une maladie, Souris knockout, Technique d'immunofluorescence, Transduction du signal, Transfection, Vaisseaux lymphatiques (anatomopathologie), Vaisseaux lymphatiques (métabolisme).
- MESH :
- anatomopathologie : Cellules endothéliales, Endothélium lymphatique, Lymphangiectasie intestinale, Lymphoedème, Malformations crâniofaciales, Vaisseaux lymphatiques.
- déficit : Cadhérines.
- génétique : Cadhérines, Lymphangiectasie intestinale, Lymphoedème, Malformations crâniofaciales, Protéines suppresseurs de tumeurs, Protéines à fluorescence verte, Protéines à homéodomaine.
- métabolisme : Actines, Cadhérines, Cellules endothéliales, Cytosquelette d'actine, Endothélium lymphatique, Lymphangiectasie intestinale, Lymphoedème, Malformations crâniofaciales, Protéines à fluorescence verte, Vaisseaux lymphatiques.
- Animaux, Cellules cultivées, Humains, Lymphangiogenèse, Mouvement cellulaire, Multimérisation de protéines, Mutation, Phénotype, Prédisposition génétique à une maladie, Souris knockout, Technique d'immunofluorescence, Transduction du signal, Transfection.
English descriptors
- KwdEn :
- Actin Cytoskeleton (metabolism), Actins (metabolism), Animals, Cadherins (deficiency), Cadherins (genetics), Cadherins (metabolism), Cell Movement, Cells, Cultured, Craniofacial Abnormalities (genetics), Craniofacial Abnormalities (metabolism), Craniofacial Abnormalities (pathology), Endothelial Cells (metabolism), Endothelial Cells (pathology), Endothelium, Lymphatic (metabolism), Endothelium, Lymphatic (pathology), Fluorescent Antibody Technique, Genetic Predisposition to Disease, Green Fluorescent Proteins (genetics), Green Fluorescent Proteins (metabolism), Homeodomain Proteins (genetics), Humans, Lymphangiectasis, Intestinal (genetics), Lymphangiectasis, Intestinal (metabolism), Lymphangiectasis, Intestinal (pathology), Lymphangiogenesis, Lymphatic Vessels (metabolism), Lymphatic Vessels (pathology), Lymphedema (genetics), Lymphedema (metabolism), Lymphedema (pathology), Mice, Knockout, Mutation, Phenotype, Protein Multimerization, Signal Transduction, Transfection, Tumor Suppressor Proteins (genetics).
- MESH :
- chemical , deficiency : Cadherins.
- chemical , genetics : Cadherins, Green Fluorescent Proteins, Homeodomain Proteins, Tumor Suppressor Proteins.
- chemical , metabolism : Actins, Cadherins, Green Fluorescent Proteins.
- genetics : Craniofacial Abnormalities, Lymphangiectasis, Intestinal, Lymphedema.
- metabolism : Actin Cytoskeleton, Craniofacial Abnormalities, Endothelial Cells, Endothelium, Lymphatic, Lymphangiectasis, Intestinal, Lymphatic Vessels, Lymphedema.
- pathology : Craniofacial Abnormalities, Endothelial Cells, Endothelium, Lymphatic, Lymphangiectasis, Intestinal, Lymphatic Vessels, Lymphedema.
- Animals, Cell Movement, Cells, Cultured, Fluorescent Antibody Technique, Genetic Predisposition to Disease, Humans, Lymphangiogenesis, Mice, Knockout, Mutation, Phenotype, Protein Multimerization, Signal Transduction, Transfection.
Abstract
The purpose of this study was to investigate the role of Fat4 and Dachsous1 signaling in the lymphatic vasculature.
DOI: 10.1161/ATVBAHA.117.309818
PubMed: 28705793
Affiliations:
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pubmed:28705793Le document en format XML
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<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<author><name sortKey="Francis West, Philippa" sort="Francis West, Philippa" uniqKey="Francis West P" first="Philippa" last="Francis-West">Philippa Francis-West</name>
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<author><name sortKey="Garmy Susini, Barbara" sort="Garmy Susini, Barbara" uniqKey="Garmy Susini B" first="Barbara" last="Garmy-Susini">Barbara Garmy-Susini</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.</title>
<author><name sortKey="Pujol, Francoise" sort="Pujol, Francoise" uniqKey="Pujol F" first="Francoise" last="Pujol">Francoise Pujol</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<author><name sortKey="Hodgson, Tina" sort="Hodgson, Tina" uniqKey="Hodgson T" first="Tina" last="Hodgson">Tina Hodgson</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
<orgName type="university">Université d'Uppsala</orgName>
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<author><name sortKey="Martinez Corral, Ines" sort="Martinez Corral, Ines" uniqKey="Martinez Corral I" first="Ines" last="Martinez-Corral">Ines Martinez-Corral</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<author><name sortKey="Prats, Anne Catherine" sort="Prats, Anne Catherine" uniqKey="Prats A" first="Anne-Catherine" last="Prats">Anne-Catherine Prats</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<author><name sortKey="Devenport, Danelle" sort="Devenport, Danelle" uniqKey="Devenport D" first="Danelle" last="Devenport">Danelle Devenport</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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<author><name sortKey="Takeichi, Masatoshi" sort="Takeichi, Masatoshi" uniqKey="Takeichi M" first="Masatoshi" last="Takeichi">Masatoshi Takeichi</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
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</author>
<author><name sortKey="Genot, Elisabeth" sort="Genot, Elisabeth" uniqKey="Genot E" first="Elisabeth" last="Genot">Elisabeth Genot</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
<orgName type="university">Université d'Uppsala</orgName>
<country>Suède</country>
<placeName><settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="M Kinen, Taija" sort="M Kinen, Taija" uniqKey="M Kinen T" first="Taija" last="M Kinen">Taija M Kinen</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
<orgName type="university">Université d'Uppsala</orgName>
<country>Suède</country>
<placeName><settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Francis West, Philippa" sort="Francis West, Philippa" uniqKey="Francis West P" first="Philippa" last="Francis-West">Philippa Francis-West</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
<orgName type="university">Université d'Uppsala</orgName>
<country>Suède</country>
<placeName><settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Garmy Susini, Barbara" sort="Garmy Susini, Barbara" uniqKey="Garmy Susini B" first="Barbara" last="Garmy-Susini">Barbara Garmy-Susini</name>
<affiliation wicri:level="4"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.).</nlm:affiliation>
<orgName type="university">Université d'Uppsala</orgName>
<country>Suède</country>
<placeName><settlement type="city">Uppsala</settlement>
<region nuts="1">Svealand</region>
<region nuts="1">East Middle Sweden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tatin, Florence" sort="Tatin, Florence" uniqKey="Tatin F" first="Florence" last="Tatin">Florence Tatin</name>
<affiliation wicri:level="1"><nlm:affiliation>From the I2MC INSERM UMR 1048, Toulouse Cedex, France (F.P., A.-C.P., B.G.-S., F.T.); Department Craniofacial Development and Stem Cell Biology, King's College London, United Kingdom (T.H., P.F.-W.); Rudbeck Laboratory, Department Immunology, Genetics and Pathology, Uppsala University, Sweden (I.M.-C., T.M.); Department of Molecular Biology, Princeton University, NJ (D.D.); Laboratory for Cell Adhesion and Tissue Patterning, RIKEN Center for Developmental Biology, Kobe, Japan (M.T.); and INSERM, Université de Bordeaux, France (E.G.). florence.tatin@inserm.fr.</nlm:affiliation>
<country wicri:rule="url">France</country>
</affiliation>
</author>
</analytic>
<series><title level="j">Arteriosclerosis, thrombosis, and vascular biology</title>
<idno type="eISSN">1524-4636</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Actin Cytoskeleton (metabolism)</term>
<term>Actins (metabolism)</term>
<term>Animals</term>
<term>Cadherins (deficiency)</term>
<term>Cadherins (genetics)</term>
<term>Cadherins (metabolism)</term>
<term>Cell Movement</term>
<term>Cells, Cultured</term>
<term>Craniofacial Abnormalities (genetics)</term>
<term>Craniofacial Abnormalities (metabolism)</term>
<term>Craniofacial Abnormalities (pathology)</term>
<term>Endothelial Cells (metabolism)</term>
<term>Endothelial Cells (pathology)</term>
<term>Endothelium, Lymphatic (metabolism)</term>
<term>Endothelium, Lymphatic (pathology)</term>
<term>Fluorescent Antibody Technique</term>
<term>Genetic Predisposition to Disease</term>
<term>Green Fluorescent Proteins (genetics)</term>
<term>Green Fluorescent Proteins (metabolism)</term>
<term>Homeodomain Proteins (genetics)</term>
<term>Humans</term>
<term>Lymphangiectasis, Intestinal (genetics)</term>
<term>Lymphangiectasis, Intestinal (metabolism)</term>
<term>Lymphangiectasis, Intestinal (pathology)</term>
<term>Lymphangiogenesis</term>
<term>Lymphatic Vessels (metabolism)</term>
<term>Lymphatic Vessels (pathology)</term>
<term>Lymphedema (genetics)</term>
<term>Lymphedema (metabolism)</term>
<term>Lymphedema (pathology)</term>
<term>Mice, Knockout</term>
<term>Mutation</term>
<term>Phenotype</term>
<term>Protein Multimerization</term>
<term>Signal Transduction</term>
<term>Transfection</term>
<term>Tumor Suppressor Proteins (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Actines (métabolisme)</term>
<term>Animaux</term>
<term>Cadhérines (déficit)</term>
<term>Cadhérines (génétique)</term>
<term>Cadhérines (métabolisme)</term>
<term>Cellules cultivées</term>
<term>Cellules endothéliales (anatomopathologie)</term>
<term>Cellules endothéliales (métabolisme)</term>
<term>Cytosquelette d'actine (métabolisme)</term>
<term>Endothélium lymphatique (anatomopathologie)</term>
<term>Endothélium lymphatique (métabolisme)</term>
<term>Humains</term>
<term>Lymphangiectasie intestinale (anatomopathologie)</term>
<term>Lymphangiectasie intestinale (génétique)</term>
<term>Lymphangiectasie intestinale (métabolisme)</term>
<term>Lymphangiogenèse</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (génétique)</term>
<term>Lymphoedème (métabolisme)</term>
<term>Malformations crâniofaciales (anatomopathologie)</term>
<term>Malformations crâniofaciales (génétique)</term>
<term>Malformations crâniofaciales (métabolisme)</term>
<term>Mouvement cellulaire</term>
<term>Multimérisation de protéines</term>
<term>Mutation</term>
<term>Phénotype</term>
<term>Protéines suppresseurs de tumeurs (génétique)</term>
<term>Protéines à fluorescence verte (génétique)</term>
<term>Protéines à fluorescence verte (métabolisme)</term>
<term>Protéines à homéodomaine (génétique)</term>
<term>Prédisposition génétique à une maladie</term>
<term>Souris knockout</term>
<term>Technique d'immunofluorescence</term>
<term>Transduction du signal</term>
<term>Transfection</term>
<term>Vaisseaux lymphatiques (anatomopathologie)</term>
<term>Vaisseaux lymphatiques (métabolisme)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Cadherins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cadherins</term>
<term>Green Fluorescent Proteins</term>
<term>Homeodomain Proteins</term>
<term>Tumor Suppressor Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Actins</term>
<term>Cadherins</term>
<term>Green Fluorescent Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Cellules endothéliales</term>
<term>Endothélium lymphatique</term>
<term>Lymphangiectasie intestinale</term>
<term>Lymphoedème</term>
<term>Malformations crâniofaciales</term>
<term>Vaisseaux lymphatiques</term>
</keywords>
<keywords scheme="MESH" qualifier="déficit" xml:lang="fr"><term>Cadhérines</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Craniofacial Abnormalities</term>
<term>Lymphangiectasis, Intestinal</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Cadhérines</term>
<term>Lymphangiectasie intestinale</term>
<term>Lymphoedème</term>
<term>Malformations crâniofaciales</term>
<term>Protéines suppresseurs de tumeurs</term>
<term>Protéines à fluorescence verte</term>
<term>Protéines à homéodomaine</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Actin Cytoskeleton</term>
<term>Craniofacial Abnormalities</term>
<term>Endothelial Cells</term>
<term>Endothelium, Lymphatic</term>
<term>Lymphangiectasis, Intestinal</term>
<term>Lymphatic Vessels</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Actines</term>
<term>Cadhérines</term>
<term>Cellules endothéliales</term>
<term>Cytosquelette d'actine</term>
<term>Endothélium lymphatique</term>
<term>Lymphangiectasie intestinale</term>
<term>Lymphoedème</term>
<term>Malformations crâniofaciales</term>
<term>Protéines à fluorescence verte</term>
<term>Vaisseaux lymphatiques</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Craniofacial Abnormalities</term>
<term>Endothelial Cells</term>
<term>Endothelium, Lymphatic</term>
<term>Lymphangiectasis, Intestinal</term>
<term>Lymphatic Vessels</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Cell Movement</term>
<term>Cells, Cultured</term>
<term>Fluorescent Antibody Technique</term>
<term>Genetic Predisposition to Disease</term>
<term>Humans</term>
<term>Lymphangiogenesis</term>
<term>Mice, Knockout</term>
<term>Mutation</term>
<term>Phenotype</term>
<term>Protein Multimerization</term>
<term>Signal Transduction</term>
<term>Transfection</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Cellules cultivées</term>
<term>Humains</term>
<term>Lymphangiogenèse</term>
<term>Mouvement cellulaire</term>
<term>Multimérisation de protéines</term>
<term>Mutation</term>
<term>Phénotype</term>
<term>Prédisposition génétique à une maladie</term>
<term>Souris knockout</term>
<term>Technique d'immunofluorescence</term>
<term>Transduction du signal</term>
<term>Transfection</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The purpose of this study was to investigate the role of Fat4 and Dachsous1 signaling in the lymphatic vasculature.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
<li>Suède</li>
</country>
<region><li>East Middle Sweden</li>
<li>Svealand</li>
</region>
<settlement><li>Uppsala</li>
</settlement>
<orgName><li>Université d'Uppsala</li>
</orgName>
</list>
<tree><country name="Suède"><region name="Svealand"><name sortKey="Pujol, Francoise" sort="Pujol, Francoise" uniqKey="Pujol F" first="Francoise" last="Pujol">Francoise Pujol</name>
</region>
<name sortKey="Devenport, Danelle" sort="Devenport, Danelle" uniqKey="Devenport D" first="Danelle" last="Devenport">Danelle Devenport</name>
<name sortKey="Francis West, Philippa" sort="Francis West, Philippa" uniqKey="Francis West P" first="Philippa" last="Francis-West">Philippa Francis-West</name>
<name sortKey="Garmy Susini, Barbara" sort="Garmy Susini, Barbara" uniqKey="Garmy Susini B" first="Barbara" last="Garmy-Susini">Barbara Garmy-Susini</name>
<name sortKey="Genot, Elisabeth" sort="Genot, Elisabeth" uniqKey="Genot E" first="Elisabeth" last="Genot">Elisabeth Genot</name>
<name sortKey="Hodgson, Tina" sort="Hodgson, Tina" uniqKey="Hodgson T" first="Tina" last="Hodgson">Tina Hodgson</name>
<name sortKey="M Kinen, Taija" sort="M Kinen, Taija" uniqKey="M Kinen T" first="Taija" last="M Kinen">Taija M Kinen</name>
<name sortKey="Martinez Corral, Ines" sort="Martinez Corral, Ines" uniqKey="Martinez Corral I" first="Ines" last="Martinez-Corral">Ines Martinez-Corral</name>
<name sortKey="Prats, Anne Catherine" sort="Prats, Anne Catherine" uniqKey="Prats A" first="Anne-Catherine" last="Prats">Anne-Catherine Prats</name>
<name sortKey="Takeichi, Masatoshi" sort="Takeichi, Masatoshi" uniqKey="Takeichi M" first="Masatoshi" last="Takeichi">Masatoshi Takeichi</name>
</country>
<country name="France"><noRegion><name sortKey="Tatin, Florence" sort="Tatin, Florence" uniqKey="Tatin F" first="Florence" last="Tatin">Florence Tatin</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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